Barry H. pylori to all antibiotics. Teams from the

Barry Marshal was
interested in pathologist, Robin Warren, studies and went to pursue in
assisting him along his research. They both went off and made very thorough observations
of the behavior gastric bacteria.            H. pylori (Hp) remains the only species of known
bacterium capable of colonizing the human stomach. Sometimes it can also infect
the duodenum in case of metaplasia (transformation of a part of the duodenum
tissue into gastric tissue). Other Helicobacter species have been identified
with other mammals and birds.            The infection may be symptomatic or asymptomatic. It is
estimated that roughly 70% of infections are asymptomatic. H. pylori can be
able to survive in stomach acid due to its secretes enzymes that neutralize the
acid. This process is called hydrolysis of urea. Thanks to its helicoidal shape
and its flagella, the bacterium slips through the mucous membranes of the
stomach and is anchored to the epithelial cells (tissue in several layers)
thanks to adhesins (fixing proteins).            Helicobacter pylori infects more than 50% of the world’s
population … Depending on the country, 20 to 90% of adult individuals are
infected. In addition, for a given country, the prevalence (ratio of the number
of cases of a disease to the size of a population) varies according to
socio-economic status. This is a very common infection. Fortunately, most
people who are infected never develop a disease symptom.            If an individual is not infected
before the age of 10, the risk of becoming infected is very low. At present,
there is no convincing argument to incriminate the environment as a source of
contamination, however lack of adequate sanitation, safe drinking water, basic
hygiene measures and Poor nutrition and overcrowding all play a role in the
global prevalence of infection.            H. pylori has been found in the
saliva of certain infected persons, it is possible that Hp can be delivered
from the stomach to the mouth via gastroesophageal reflux, and then transmitted
by oral contact as the embrace.            By culturing tissues supposedly
contaminated by the microorganism. Culture is the reference method for
identifying H. pylori. This method makes it possible to determine the
sensitivity of H. pylori to all antibiotics.

            Teams from the Institut Pasteur are
specialized in the study of the bacterium Helicobacter pylori and its role in
the development of gastric pathologies. There are several international
recommendations on the management of Helicobacter. The most recent European
consensus at the time of writing this article is: Management of H. Pylori
Infection.

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