One influence on reproductive functions, wound regeneration and antidiabetic

     One of the most valuable components of indigenous medical systems for
over 40 centuries has been Mangifera indica
leaves, the largest fruit-bearing tree ever discovered in India. The
usage of Mangifera indica leaves as a
medicinal agent dates back to as early as 327 BCE.
The presence of some major groups of phytochemical constituents such as
saponins, anthraquinones, terpenoids, etc. and therapeutically active
components such as mangiferin,
stigmasterol, friedelin, lupeol, etc. have
also been reported from Mangifera indica leaves.


There is a scarcity of scientific information in support of their
success, whilst the leaves have been traditionally used as an antibacterial and immunomodulatory agent. Mangifera indica
leaves are also used as an antibacterial agent in Nigerian folk herbalism. To ascertain whether or not there is
a scientific basis for this use, the
effect of the blood glucose level was evaluated in
normoglycaemic, glucose-induced hyperglycaemic and streptozotocin (STZ) induced diabetic rodents such as Rattus (rat).
The aqueous extract given orally did not modify the blood glucose levels in
either normoglycaemic or STZ-induced (streptozotocin) diabetic rodents
specifically Rattus (rat).

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Aqueous extracts of Mangifera indica leaves showed remarkable influence on reproductive functions,
wound regeneration and antidiabetic tasks. Alcoholic extracts of Mangifera
indica leaves have been found containing TNF- (Tumor necrosis factor), ILIB
expression and B-lactamase producing enteric
bacterial development.


     Mangifera indica leaves are equipped with
a broad outer cuticle to avoid the loss of nutrients
and to prevent wetting when it’s
raining. Furthermore, Mangifera indica
leaves are found alternating on the plant stalk to exploit the light energy acquired from the sun. This is because of the
fact that Mangifera indica develops best when exposed to sunlight.